Imperial College of Science, Technology and Medicine

London, UK

Imperial College of Science, Technology and Medicine is one of the leading scientific universities in the world (currently as 3rd in Europe and 8th in the world). Imperial’s School of Public Health (ISPH) is an organizational leader in public health research, as evidenced by the 2014 Research Assessment Exercise, where it was in the top two ranking departments nationally for public health. ISPH hosts the MRC Centre for Environment and Health. Research at the MRC Centre focusses on the study of the health effects of ubiquitous environmental hazards of major public health and scientific importance, such as air pollution, noise pollution, non-ionising radiation and other agents. The Centre’s research is grouped in five complementary themes, from research on Environmental Pollutants, Exposome and Healthy Cities, to Biostatistics and Cohort studies. The Centre’s activities also include leading programmes on Training and Policy Translation. The MRC Centre for Environment and Health undertakes the highest quality research in the fields of environment and health, to inform health policy and the understanding of key issues affecting our society. The Centre achieves this by bringing together the best researchers from all areas of public health, encouraging novel cross-disciplinary approaches, and by providing the highest quality training to new and existing researchers in these fields.  The MRC Centre incorporates state of the art omics platforms: genomics including microarray gene expression, RNA Seq, DNA sequencing; cutting-edge metabolomics (Phenome Center); metagenomics DNA, RNA and metabolites of the microbiome; epigenomics and epigenomic epidemiology; systems biology, including of airway differentiation and inflammation; and expertise in cellular biology.

Role in the project

ICL will bring expertise in molecular and environmental epidemiology to the project. ICL will be contributing data from adults cohorts, including the EPIC and AIRWAVE studies for WP1 and WP5. ICL will lead the following tasks: task 1.5 regarding exposure to EDCs and risk of autoimmune diseases based on new exposure biomarker measurements in a case-cohort study; task  5.4 regarding endogenous metabolic mechanisms of EDC-triggered immune-mediated health outcomes; and task 6.2, Weight-of-Evidence approach to evidence synthesis of human and  experimental data for strengthening causal inference.


Oliver Robinson

Dr. Oliver Robinson is a lecturer in molecular Epidemiology and UKRI Future Leaders Fellow. His interests lie in life-course epidemiology, biological ageing and the exposome. He has been involved in many large scale European exposome projects, including HELIX, Exposomics, Lifepath and STOP projects. He currently leads a project developing novel molecular biomarkers of ageing using omics technologies and investigates risk factors of accelerated ageing. He has authored over 90 publications and is a member of the MRC Centre for Environment and Health at Imperial College London, where he is researching effects of air pollution on epigenetic ageing and metabolomic markers and their role in dementia risk.

Paolo Vineis

Professor Paolo Vineis is a leading researcher in the fields of molecular epidemiology and non-communicable diseases (NCD). He is Chair of Environmental Epidemiology at Imperial College, London. He is ranked in the top 10 most cited Imperial College scientists with nearly 140,000 citations (H-index 173). His latest research activities focus on investigating biomarkers from omic platforms (including metabolomics and epigenetics) in large epidemiological studies. He has more than 1,100 publications (many as leading author) in journals such as Nature, Science, Lancet, Lancet Oncology. He is a member of various international scientific committees and the Ethics Committee at the International Agency for Research on Cancer (IARC, WHO). Professor Vineis has extensive experience in leading international projects. He has coordinated the European Commission FP7-funded Exposomics project and the Horizon 2020-funded project Lifepath. He has been the director of the Unit of Molecular and Genetic Epidemiology at the Italian Institute for Genomic Medicine, Torino, Italy and leads the “Molecular signatures and pathways to disease” (Exposome) theme of the MRC Centre for Environment and Health at Imperial College